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BIMPM1: Precision Medicine

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BIMPM1: Precision Medicine

Module code: BIMPM1

Module provider: School of Biological Sciences

Credits: 20

Level: Postgraduate Masters

When you'll be taught: Semester 1

Module convenor: Dr Mike Fry, email: m.j.fry@reading.ac.uk

Module co-convenor: Professor Phillip Dash, email: p.r.dash@reading.ac.uk

Pre-requisite module(s):

Co-requisite module(s):

Pre-requisite or Co-requisite module(s):

Module(s) excluded:

Placement information: NA

Academic year: 2024/5

Available to visiting students: No

Talis reading list: No

Last updated: 23 May 2024

Overview

Module aims and purpose

In this module students will learn how developments in genomics and multiomics technologies have changed our understanding of disease and allowed a more patient-focused approach to treatment – precision medicine – to be developed. Students will learn the principles of genomics and multiomics technologies and how they can be used to guide treatment. Students will also learn about the role of biomarkers in precision medicine and the importance of biomarker discovery. They will learn about the role of genomic information in predicting drug response – pharmacogenomics – and how this can help avoid adverse drug reactions. Finally, students will learn about targeted treatments such as small molecule signal transduction inhibitors and antibody-based therapies. Case studies from industry will be used to discuss key concepts in precision medicine. 

Module learning outcomes

By the end of the module, it is expected that students will be able to: 

  1. Demonstrate an understanding of the fundamental concepts and principles of precision medicine. 
  2. Critically evaluate the role of genomics, proteomics, metabolomics, and other omics technologies in precision medicine. 
  3. Analyse the impact of genetic and epigenetic variations on disease susceptibility, disease progression, and response to treatments. 
  4. Assess the potential applications of precision medicine in the diagnosis, prognosis, and treatment of various diseases. 
  5. Understand the challenges associated with the implementation of precision medicine in healthcare. 

Module content

  • Introduction to omics technologies and their use in personalised medicine. 
  • Biomarker discovery and use of biomarkers in clinical research. 
  • Introduction to pharmacogenomics. 
  • Targeted therapies. 
  • Precision medicine in practice. 

Structure

Teaching and learning methods

Teaching will be delivered through formal lectures and seminars in which students will discuss key concepts in precision medicine with the aid of case studies provided by industry. Students will also be expected to learn through self-directed study and through group working. Learning will be assessed by a presentation and an in-class test. 

Study hours

At least 34 hours of scheduled teaching and learning activities will be delivered in person, with the remaining hours for scheduled and self-scheduled teaching and learning activities delivered either in person or online. You will receive further details about how these hours will be delivered before the start of the module.


 Scheduled teaching and learning activities  Semester 1  Semester 2 Ìý³§³Ü³¾³¾±ð°ù
Lectures 22
Seminars 12
Tutorials
Project Supervision
Demonstrations
Practical classes and workshops
Supervised time in studio / workshop
Scheduled revision sessions
Feedback meetings with staff
Fieldwork
External visits
Work-based learning


 Self-scheduled teaching and learning activities  Semester 1  Semester 2 Ìý³§³Ü³¾³¾±ð°ù
Directed viewing of video materials/screencasts
Participation in discussion boards/other discussions
Feedback meetings with staff
Other
Other (details)


 Placement and study abroad  Semester 1  Semester 2 Ìý³§³Ü³¾³¾±ð°ù
Placement
Study abroad

Please note that the hours listed above are for guidance purposes only.

 Independent study hours  Semester 1  Semester 2 Ìý³§³Ü³¾³¾±ð°ù
Independent study hours 166

Please note the independent study hours above are notional numbers of hours; each student will approach studying in different ways. We would advise you to reflect on your learning and the number of hours you are allocating to these tasks.

Semester 1 The hours in this column may include hours during the Christmas holiday period.

Semester 2 The hours in this column may include hours during the Easter holiday period.

Summer The hours in this column will take place during the summer holidays and may be at the start and/or end of the module.

Assessment

Requirements for a pass

Students need to achieve an overall module mark of 50% to pass this module.

Summative assessment

Type of assessment Detail of assessment % contribution towards module mark Size of assessment Submission date Additional information
Oral assessment Presentation 50
Set exercise Problem sheet 50

Penalties for late submission of summative assessment

The Support Centres will apply the following penalties for work submitted late:

Assessments with numerical marks

  • where the piece of work is submitted after the original deadline (or any formally agreed extension to the deadline): 10% of the total marks available for that piece of work will be deducted from the mark for each working day (or part thereof) following the deadline up to a total of three working days;
  • the mark awarded due to the imposition of the penalty shall not fall below the threshold pass mark, namely 40% in the case of modules at Levels 4-6 (i.e. undergraduate modules for Parts 1-3) and 50% in the case of Level 7 modules offered as part of an Integrated Masters or taught postgraduate degree programme;
  • where the piece of work is awarded a mark below the threshold pass mark prior to any penalty being imposed, and is submitted up to three working days after the original deadline (or any formally agreed extension to the deadline), no penalty shall be imposed;
  • where the piece of work is submitted more than three working days after the original deadline (or any formally agreed extension to the deadline): a mark of zero will be recorded.

Assessments marked Pass/Fail

  • where the piece of work is submitted within three working days of the deadline (or any formally agreed extension of the deadline): no penalty will be applied;
  • where the piece of work is submitted more than three working days after the original deadline (or any formally agreed extension of the deadline): a grade of Fail will be awarded.

The University policy statement on penalties for late submission can be found at: /cqsd/-/media/project/functions/cqsd/documents/qap/penaltiesforlatesubmission.pdf

You are strongly advised to ensure that coursework is submitted by the relevant deadline. You should note that it is advisable to submit work in an unfinished state rather than to fail to submit any work.

Formative assessment

Formative assessment is any task or activity which creates feedback (or feedforward) for you about your learning, but which does not contribute towards your overall module mark.

Seminars will provide students with an opportunity to gain feedback on their understanding of the topics covered in the module. 

Reassessment

Type of reassessment Detail of reassessment % contribution towards module mark Size of reassessment Submission date Additional information
Written coursework assignment Essay 100

Additional costs

Item Additional information Cost
Computers and devices with a particular specification
Required textbooks
Specialist equipment or materials
Specialist clothing, footwear, or headgear
Printing and binding
Travel, accommodation, and subsistence

THE INFORMATION CONTAINED IN THIS MODULE DESCRIPTION DOES NOT FORM ANY PART OF A STUDENT'S CONTRACT.

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